Phospho-HDAC1 (Ser421, Ser423) Polyclonal Antibody 试剂_100 μL

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100 μL

RH462668

PA5-36911

1kg单位：瓶

14品 牌：Invitrogen

0

产品详细信息

This antibody detects endogenous protein at a molecular weight of 55 kDa.

Purity is >95% by SDS-PAGE.

靶标信息

Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. HDAC1 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, HDAC1 deacetylates p53 and modulates its effect on cell growth and apoptosis.

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